Overview

SCIENTIFIC SCORE
Questionable
Based on 2 Researches
5
USERS' SCORE
Good
Based on 22 Reviews
8.5
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Vitamin D3 (as cholecalciferol)
125 mcg
625%
Vitamin K activity from:Vitamin K1 (as phytonadione)Vitamin K2 (as menaquinone-4)Vitamin K2 (as trans menaquinone-7)
2,100 mcg1,000 mcg1,000 mcg100 mcg
1,750%
Iodine [from Sea-Iodine™ Complex Blend (organic kelp and bladderwrack extracts, potassium iodide)]
1,000 mcg
667%

Top Medical Research Studies

We conducted a thorough investigation into whether high-dose intermittent vitamin D3 could alleviate symptoms of chronic fatigue syndrome (CFS) and improve vascular health. This double-blind, randomized placebo-controlled trial involved patients meeting established criteria for CFS. Participants received either 100,000 units of vitamin D3 or a placebo every two months for six months.

Over the course of the study, we measured key outcomes such as arterial stiffness, blood pressure, cholesterol levels, and fatigue levels through various tests. Surprisingly, our findings showed that vitamin D3 treatment did not lead to any significant improvements in these areas. We observed only a slight increase in vitamin D levels in the treatment group, but this did not translate into better vascular health or reduced fatigue.

In conclusion, we honestly found that high-dose vitamin D3 did not offer any notable benefits for patients struggling with chronic fatigue syndrome. This study highlights the complexities of treating CFS and suggests that vitamin D3 may not be the solution some had hoped for.
Read More
8
Beta-glucan shows cognitive improvements
We conducted a randomized, double-blind, placebo-controlled trial to explore how yeast beta-glucan, along with multivitamins, affects individuals suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). In our study, 65 participants received either beta-glucan combined with vitamins and zinc or a placebo for 36 weeks.

Interestingly, while our primary focus was on beta-glucan, which was shown to significantly improve cognitive fatigue, the role of vitamin D3 within this combination was not clearly established. This makes it challenging to directly assess the impact of vitamin D3 alone on chronic fatigue syndrome outcomes.

Overall, we discovered that beta-glucan supplementation could positively influence cognitive fatigue, offering promise for future research on nutritional support in ME/CFS patients. However, definitive conclusions about vitamin D3's effectiveness remain inconclusive due to the combined nature of the treatment.
Read More

Most Useful Reviews

9
Improved energy levels
91 people found this helpful
I've been taking this vitamin for 3 months and can see the difference. My quality of life has improved immensely, with no more fatigue or lack of motivation to get out of bed. I feel more energised, can concentrate better, and my mood has significantly improved. I highly recommend it.
Read More
9
Fatigue vanished
28 people found this helpful
Good product! I take it with selenium, zinc, iron, and vitamin C. I noticed the effects within 2 weeks. Chronic fatigue vanished, and I have significantly more energy. If my review was helpful, please give a thumbs up!
Read More
9
Fatigue resolved
19 people found this helpful
It works! After 8 months of constant fatigue, lethargy, and apathy, I couldn't even enjoy a holiday. Following a friend's advice to check my vitamin D, I discovered I had a deficiency. After taking this product for 2 weeks, all my fatigue disappeared, and I can now truly enjoy life again. I highly recommend it!
Read More

Medical Researches

SCIENTIFIC SCORE
Questionable
Based on 2 Researches
5
  • All Researches
8
Beta-glucan shows cognitive improvements
We conducted a randomized, double-blind, placebo-controlled trial to explore how yeast beta-glucan, along with multivitamins, affects individuals suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). In our study, 65 participants received either beta-glucan combined with vitamins and zinc or a placebo for 36 weeks.

Interestingly, while our primary focus was on beta-glucan, which was shown to significantly improve cognitive fatigue, the role of vitamin D3 within this combination was not clearly established. This makes it challenging to directly assess the impact of vitamin D3 alone on chronic fatigue syndrome outcomes.

Overall, we discovered that beta-glucan supplementation could positively influence cognitive fatigue, offering promise for future research on nutritional support in ME/CFS patients. However, definitive conclusions about vitamin D3's effectiveness remain inconclusive due to the combined nature of the treatment.
Read More
We conducted a thorough investigation into whether high-dose intermittent vitamin D3 could alleviate symptoms of chronic fatigue syndrome (CFS) and improve vascular health. This double-blind, randomized placebo-controlled trial involved patients meeting established criteria for CFS. Participants received either 100,000 units of vitamin D3 or a placebo every two months for six months.

Over the course of the study, we measured key outcomes such as arterial stiffness, blood pressure, cholesterol levels, and fatigue levels through various tests. Surprisingly, our findings showed that vitamin D3 treatment did not lead to any significant improvements in these areas. We observed only a slight increase in vitamin D levels in the treatment group, but this did not translate into better vascular health or reduced fatigue.

In conclusion, we honestly found that high-dose vitamin D3 did not offer any notable benefits for patients struggling with chronic fatigue syndrome. This study highlights the complexities of treating CFS and suggests that vitamin D3 may not be the solution some had hoped for.
Read More

User Reviews

USERS' SCORE
Good
Based on 22 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Improved energy levels
91 people found this helpful
I've been taking this vitamin for 3 months and can see the difference. My quality of life has improved immensely, with no more fatigue or lack of motivation to get out of bed. I feel more energised, can concentrate better, and my mood has significantly improved. I highly recommend it.
Read More
9
Fatigue vanished
28 people found this helpful
Good product! I take it with selenium, zinc, iron, and vitamin C. I noticed the effects within 2 weeks. Chronic fatigue vanished, and I have significantly more energy. If my review was helpful, please give a thumbs up!
Read More
9
Fatigue resolved
19 people found this helpful
It works! After 8 months of constant fatigue, lethargy, and apathy, I couldn't even enjoy a holiday. Following a friend's advice to check my vitamin D, I discovered I had a deficiency. After taking this product for 2 weeks, all my fatigue disappeared, and I can now truly enjoy life again. I highly recommend it!
Read More
9
Energy restored
10 people found this helpful
I have not used salt for seven years, leading to iodine deficiency. With this supplement, the fatigue I experienced upon waking subsided, and I no longer feel sleepy at work. My energy has returned.
Read More
7.5
Symptoms alleviated
6 people found this helpful
I previously suffered from tiredness and fatigue due to low vitamin D levels. After taking it, those symptoms disappeared. I plan to continue using it, although the price is a bit high.
Read More

Frequently Asked Questions

9
Fatigue vanished
28 people found this helpful
Good product! I take it with selenium, zinc, iron, and vitamin C. I noticed the effects within 2 weeks. Chronic fatigue vanished, and I have significantly more energy. If my review was helpful, please give a thumbs up!
9
Fatigue resolved
19 people found this helpful
It works! After 8 months of constant fatigue, lethargy, and apathy, I couldn't even enjoy a holiday. Following a friend's advice to check my vitamin D, I discovered I had a deficiency. After taking this product for 2 weeks, all my fatigue disappeared, and I can now truly enjoy life again. I highly recommend it!
7.5
Positive effects noted
1 people found this helpful
The feeling of constant fatigue has diminished since I started taking these vitamins a month ago. I believe there is a positive trend. Prior to my tests, my vitamin D level was 15. The fatigue seems to be lifting.
9
Improved energy levels
91 people found this helpful
I've been taking this vitamin for 3 months and can see the difference. My quality of life has improved immensely, with no more fatigue or lack of motivation to get out of bed. I feel more energised, can concentrate better, and my mood has significantly improved. I highly recommend it.
9
Depression alleviated
My fatigue and depression have vanished, which is very significant for me. I take these in combination with Omega. It’s a fantastic product.
7.5
Boost in energy
1 people found this helpful
Important!!! Why the addition of vitamin K? An endocrinologist advised taking vitamin D with K. For ages, I sought this dosage of 5,000 with vitamin K and found it with this manufacturer. Overall, I am satisfied with the quality. The small capsules are easy to swallow and have no side effects. I advise taking them in the morning with breakfast. After taking one capsule, I feel well, experience more energy, and notice a reduction in fatigue.
7.5
Less lethargy
The doctor prescribed two pills daily, which the bank provided quickly. After repeated tests over several months, my vitamin D level improved significantly. There was previously fatigue and lethargy during the day, but it is now easier to wake up without feeling heavy. However, the positive effects seemed to diminish, suggesting a longer intake may be needed.
We conducted a thorough investigation into whether high-dose intermittent vitamin D3 could alleviate symptoms of chronic fatigue syndrome (CFS) and improve vascular health. This double-blind, randomized placebo-controlled trial involved patients meeting established criteria for CFS. Participants received either 100,000 units of vitamin D3 or a placebo every two months for six months.

Over the course of the study, we measured key outcomes such as arterial stiffness, blood pressure, cholesterol levels, and fatigue levels through various tests. Surprisingly, our findings showed that vitamin D3 treatment did not lead to any significant improvements in these areas. We observed only a slight increase in vitamin D levels in the treatment group, but this did not translate into better vascular health or reduced fatigue.

In conclusion, we honestly found that high-dose vitamin D3 did not offer any notable benefits for patients struggling with chronic fatigue syndrome. This study highlights the complexities of treating CFS and suggests that vitamin D3 may not be the solution some had hoped for.
8
Beta-glucan shows cognitive improvements
We conducted a randomized, double-blind, placebo-controlled trial to explore how yeast beta-glucan, along with multivitamins, affects individuals suffering from Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS). In our study, 65 participants received either beta-glucan combined with vitamins and zinc or a placebo for 36 weeks.

Interestingly, while our primary focus was on beta-glucan, which was shown to significantly improve cognitive fatigue, the role of vitamin D3 within this combination was not clearly established. This makes it challenging to directly assess the impact of vitamin D3 alone on chronic fatigue syndrome outcomes.

Overall, we discovered that beta-glucan supplementation could positively influence cognitive fatigue, offering promise for future research on nutritional support in ME/CFS patients. However, definitive conclusions about vitamin D3's effectiveness remain inconclusive due to the combined nature of the treatment.

References

  1. Lacasa M, Alegre-Martin J, Sentañes RS, Varela-Sende L, Jurek J, et al. Yeast Beta-Glucan Supplementation with Multivitamins Attenuates Cognitive Impairments in Individuals with Myalgic Encephalomyelitis/Chronic Fatigue Syndrome: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2023;15. 10.3390/nu15214504
  2. Witham MD, Adams F, McSwiggan S, Kennedy G, Kabir G, et al. Effect of intermittent vitamin D3 on vascular function and symptoms in chronic fatigue syndrome--a randomised controlled trial. Nutr Metab Cardiovasc Dis. 2015;25:287. 10.1016/j.numecd.2014.10.007
image